Soulstone Survivors Negative Effects and Power-Ups

Here's a list of all the Negative Effects and Synergy Power-Ups in Soulstone Survivors.

Soulstone Survivor has a lot of different skill modifiers and power-ups, so much so that it can be a little overwhelming figuring out how all of them work. One of the more confusing modifiers is “negative effects,” which are basically status ailments. In this guide, we’ll go over all of the negative effects and synergy power-ups in Soulstone Survivors.

Learn more about how to maximize Negative Effects using the Synergetic Rune.

Soulstone Survivors Negative Effects

These are the Negative Effects in Soulstone Survivors:

  • Poison
  • Fragility
  • Burn
  • Doom
  • Slow
  • Wound
  • Bleed

Soulstone Survivors Synergy Power-Ups

These are the synergy power-ups in Soulstone Survivors:

  • Thermal Shock: Every time you apply a stack of Burn, there is a 70% chance of applying Slow as well.
  • Hypothermia: Every time you apply a stack of Slow, there is a 70% chance of applying Fragility as well.
  • Gangrene: Every time you apply a stack of Fragility, there is a 70% chance of applying Bleed as well.
  • Poisonous Blood: Every time you apply a stack of Bleed, there is a 70% chance of applying Poison as well.
  • Debilitating Plague: Every time you apply a stack of Poison, there is a 70% chance of applying Doom as well.
  • Impending Doom: Every time you apply a stack of Doom, there is a 70% chance of applying Dazed as well.
  • Desperation: Every time you apply a stack of Dazed, there is a 70% chance of applying Burn as well.
  • Brutal Strikes: Your critical strikes have a 50% chance of applying Bleed to the target.
  • Expose Weaknesses: Your critical strikes have a 100% chance of applying Wound to the target.
  • Venomous: All your attacks have a 30% chance of applying Poison to the target.
  • Frailty: All your attacks have a 10% chance of applying Fragility to the target.
  • Spontaneous Combustion: All your attacks have a 25% chance of applying Burn to the target.
  • Fateful Strikes: All your attacks have a 20% chance of applying Doom to the target.
  • Touch of Ice: All your attacks have a 40% chance of applying Slow to the target.

Negative Effects Synergy Builds

You can think of all the synergy power-ups, sans Brutal Strikes and Expose Weakness, as a carousel. By getting Thermal Shock, you have a chance to apply Slow, and by having Hypothermia, that Slow has a chance to apply Fragility, which has a chance to activate Gangrene and apply Bleed, and so forth. 

A “negative effects build” aims to complete the circle and have all of the power-ups for maximum synergy. Chaos Skills are great because they have a chance to apply a random powerful Negative Effect on the enemy. Chromatic Bolt is also good, as it’s a skill that has every spell-type attached to it, including Chaos. On top of that, you should also run the Synergetic, Controlled Chaos, and Executioner Runes:

  • Synergetic: Increases chance of getting synergy power-ups and chance of synergies happening by 20%.
  • Controlled Chaos: Abilities that deal random damage have the damage rolled, and the highest damage roll is chosen.
  • Executioner: Enemies take 5% extra damage per different types of negative effects on them.

For more content and guides, visit our Soulstone Survivors Section.